Mulazzo's center is still perfectly preserved and witnesses a past rich in history. The strategic position of the village attracted the interest of the Byzantines, who used the place to control the formidable Longobards coming from north. These latter eventually conquered the town but then, for political reasons, preferred to donate it to the marquis Obizzo Malaspina.

The power of the Malaspina family was particularly strong on this area. At the beginning of XIV century Franceschino Malaspina was patronising a number of artists and intellectuals; among them the famous Dante Alighieri. The poet, who was also an important personality in politics, spent a long period in Mulazzo, mediating the peace between the Malaspina and the bishop of Luni. At the same time, when he was in Mulazzo, he wrote part of his Commedia.

Later Mulazzo was under the rule of the French, who ensured political stability but were unable to develop the area economically. After the Vienna Congress a period of relative instability followed, as some parties in the area of Mulazzo were faithful to the Regno di Sardegna, while others tried to maintain some independence. Later, as the Regno di Sardegna strengthened its authority and then became "Regno d'Italia", the situation regularised.